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A May 1952 poster, designed by the PRC's Propaganda Department of the Central Ministry of Health & the All-China Artists Association, illustrates efforts undertaken to respond to US bioweapons attack
Eosinophil-associated disorders can affect practically all tissues and organs in the body, either individually or in combination. This article provides an overview of end-organ manifestations of eosinophilia, discussing selected organ systems ...
“The majority of probationary employees in my office have been with the agency for 10+ years and just got new positions,” said one worker who still had their job, and who spoke to the Guardian under the condition of anonymity for fear of reprisal. “If we lose them, we’re losing not just the world-class work they do day to day but also decades of expertise and institutional knowledge.”
A new report shows many Democratic lawmakers are simply ignoring their constituents’ phone calls about the humanitarian catastrophe in Gaza.
Background Eosinophilic gastrointestinal diseases (EGIDs) are chronic immune-mediated inflammatory disorders characterized by gastrointestinal symptoms and eosinophilic inflammation in specific regions of the gastrointestinal tract. “Eosinophilic gastritis” (EoG) refers to the condition in which the stomach is involved. In patients with EoG, approved treatment options are restricted despite the high mortality associated with the condition. Dupilumab is a human monoclonal antibody directed against the interleukin (IL)-4 receptor α subunit and inhibits the signaling pathways of both IL-4 and IL-13. The real-world data on the effectiveness of dupilumab for EoG are limited. We present the case of a patient with EoG and accompanying severe asthma who demonstrated improvement with dupilumab administration. Case presentation A 35-year-old woman who had been treated for asthma complained of worsening intermittent upper abdominal pain. Her dyspnea aggravated and she was admitted to our hospital for asthma exacerbation. Despite the improvement in her asthma symptoms with systemic corticosteroids, her abdominal pain persisted. Upper gastrointestinal endoscopic mucosal biopsy revealed eosinophilic cell infiltration; therefore, the patient was diagnosed with EoG. Dupilumab administration was initiated for asthma, while improvement of secondary EoG was expected. Following dupilumab administration, both EoG and asthma symptoms, disease control, laboratory findings, endoscopic findings, and pathological findings improved. No adverse events have been reported after the dupilumab treatment. Conclusion This case report supports that dupilumab could be an effective treatment option for EoG and accompanying severe asthma.
The Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR) is dedicated to improving people's life with eosinophilic gastrointestinal disorders.
Eosinophilic gastrointestinal disease (EGID) is an emerging condition worldwide in both children and adults, although it is considered rare. EGID has been underestimated owing to its underdiagnosis in the past, and its prevalence has recently ...
Two U.S. nonprofits that manufacture a treatment sent by USAID to help severely malnourished children abroad say the process is in chaos. This isn’t what Marco Rubio said would happen.
The Federal Aviation Administration has agreed to use SpaceX’s Starlink internet system to upgrade the information technology networks it uses to manage US airspace, raising new concerns about conflicts of interest for CEO Elon Musk in one of his other roles, that of recommending funding cuts at federal agencies, including the FAA.
Elon Musk said he is “almost always” sober during his late-night — or, in some cases, very early morning — posting sessions on his social media platform, X.
Helping those who want to leave Scientology and the Sea Org, but who lack a system of support that they can rely on.
The Bureau of Prisons is moving forward with plans to move transgender inmates out of prisons that align with their gender identity and into facilities that align with their assigned<strong> </strong>sex at birth.
Net zero policies would result in fewer deaths saving UK billions, say researchers