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Negative experiences, such as being bullied or socially isolated, may lead to hallucinations.
This cohort study evaluates whether there is an association between 1 year of cannabis use for medical symptoms and brain activation during working memory, reward, and inhibitory control tasks.
Scientists and Economists Alert! Global Emergency Compounded by the AIDS-like Features of SARS-CoV-2 Infection Over a million people in the US are being infected with severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) every day. Originally named after the acute respiratory syndrome it can cause as a consequence of blood vessel damage in the lungs, … Continued
“When I die, please don’t say that I’ve crossed over into the spirit realm, gone to the Other Side, moved on to a better place, rejoined my ancestors, or any other of those comforting fables,” he wrote. “Just selfishly or selflessly use my own impermanence to WAKE UP to your own.”
Life-threatening thrombotic events and neurological symptoms are prevalent in COVID-19 and are persistent in patients with long COVID experiencing post-acute sequelae of SARS-CoV-2 infection1,2,3,4. Despite the clinical evidence1,5,6,7, the underlying mechanisms of coagulopathy in COVID-19 and its consequences in inflammation and neuropathology remain poorly understood and treatment options are insufficient. Fibrinogen, the central structural component of blood clots, is abundantly deposited in the lungs and brains of patients with COVID-19, correlates with disease severity and is a predictive biomarker for post-COVID-19 cognitive deficits1,5,8,9,10. Here we show that fibrin binds to the SARS-CoV-2 spike protein, forming proinflammatory blood clots that drive systemic thromboinflammation and neuropathology in COVID-19. Fibrin, acting through its inflammatory domain, is required for oxidative stress and macrophage activation in the lungs, whereas it suppresses natural killer cells, after SARS-CoV-2 infection. Fibrin promotes neuroinflammation and neuronal loss after infection, as well as innate immune activation in the brain and lungs independently of active infection. A monoclonal antibody targeting the inflammatory fibrin domain provides protection from microglial activation and neuronal injury, as well as from thromboinflammation in the lung after infection. Thus, fibrin drives inflammation and neuropathology in SARS-CoV-2 infection, and fibrin-targeting immunotherapy may represent a therapeutic intervention for patients with acute COVID-19 and long COVID.
In the years since the alleged death of beloved accessibility advocate Susan Banks, mounting evidence and accounts from those close to her work suggest that she was not the person she claimed to be. In fact, some are convinced that Banks may never have existed at all.
Researchers have analyzed crop yields of more than 1,500 fields on six continents and found that a lack of pollinators is limiting the production worldwide of important, nutritionally dense foods such as fruits, vegetables, nuts and legumes.
New York University is creating a dangerous precedent that can be used to squash campus protests against Israel’s war on Gaza.
The judge also threw out major felony charges against two former Louisville police officers accused of falsifying a warrant.
Donald Trump has found a lucrative way to channel millions in campaign donations directly into his own businesses, raising significant concerns about the intertwining of his political influence and personal profit. An investigation has uncovered a striking pattern of former President Donald Trump redirecting millions of campaign dollars into his own businesses.
Vice President Kamala Harris accepted the Democratic nomination Thursday after a four-day convention in Chicago where her campaign refused to allow a Palestinian American to take the stage to address Israel’s war on Gaza. We hear Georgia state Representative Ruwa Romman, who was among the list of speakers offered by the Uncommitted National Movement that the Harris campaign rejected, reading the speech she would have given on the convention floor had the DNC and the Harris campaign allowed her onstage.
Crochet your own adorable ghost walking a ghost dog amigurumi! Easy-to-follow pattern inspired by the viral TikTok trend. Perfect Halloween decor.
The global pro-Palestinian movement must not fall for short-term goals that do not address Palestinian demands.
Israel has caused countless preventable deaths which are yet to be reflected in the official Gaza death toll.